Brain MRI Depiction of Multiple Cranial Neuropathies in Neurosarcoidosis: A Case Report

Ken Ikeda, Naoyuki Kawagoe, Takehisa Hirayama, Tetsuro Nagaoka, Konosuke Iwamoto, Osamu Kano, Kiyokazu Kawabe, Yasuo Iwasaki


We report depiction of brain MRI lesions in a 33-year-old woman with multiple cranial neuropathies (II, III, V, VII, VIII, IX and X) due to neurosarcoidosis. She developed the right facial nerve palsy and vestibulopathy. MRI disclosed gadolinium-enhancement in the right geniculate ganglion and VIII cranial nerve. One week later, she had motor palsy of the left VII, IX and X cranial nerves, and hypoesthesia in the left V2and V3regions. Gadolinium-enhancing lesions were found in the bilateral IX and X cranial nerves, the pontine leptomeninges and the fourth ventricle. These neuroradiological hallmarks displayed that widespread basal meningitis and inflammation of the cranial nerves could contribute to the crucial pathogenesis of multiple cranial neuropathies in neurosarcoidosis.

J Neurol Res. 2011;1(3):121-123


Neurosarcoidosis; Multiple cranial neuropathy; Basal meningitis; MRI; Gadolinium enhancement

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