Chordoid Glioma of Third Ventricle Presenting as Primary Polydipsia With Aggressive Behavior: A Rare Case With Rare Presentation

Abhinav Kumar Gupta, Deepak Chand Gupta, Saqib Ahmad Khan, Mohd. Razi Syed, Puneet Gupta, Keshav Kumar Gupta


Chordoid glioma of third ventricle is relatively rare and characterized by unique histomorphology and varied clinical presentation. Chordoid glioma has high morbidity and high mortality rates despite being low grade tumor because of insidious presentation and difficulty in complete resection. Here, we report a new case of chordoid glioma occurring in a 32-year-old male, who presented with polyuria, polydipsia and behavioral problems, and on the water deprivation test diagnosis of primary polydipsia was made. MRI revealed tumor of third ventricle, which was resected subtotally. Diagnosis of chordoid glioma was confirmed by histology and immunohistochemical analysis of resected tumor. Recurrence of chordoid glioma was reported on MRI after 2.5 months. Based on this case report, we suggest chordoid glioma should be kept in differential diagnosis of primary polydipsia.

J Neurol Res. 2017;7(4-5):85-88


Chordoid glioma; Primary polydipsia; Hypothalamic dysfunction; Endocrine dysfunction

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