Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website http://www.neurores.org

Case Report

Volume 10, Number 1, February 2020, pages 13-16


Atypical Teratoid/Rhabdoid Tumor of the Sellar Region: A Case Report and Review of the Literature

Figures

Figure 1.
Figure 1. (a) T1-weighted MRI sagittal images showing large intrasellar mass (arrow), (b) T1-weighted MRI coronal images showing large intrasellar mass encasing right internal carotid artery (arrow). MRI: magnetic resonance imaging.
Figure 2.
Figure 2. The tumor is composed of sheets of undifferentiated cells with large area of necrosis and hemorrhage (H&E stain, × 200 magnifications). H&E: hematoxylin and eosin stain.
Figure 3.
Figure 3. The tumor is composed of medium sized to large cells with prominent nucleoli and some with peripherally placed nuclei (H&E stain, × 400 magnifications). H&E: hematoxylin and eosin stain.
Figure 4.
Figure 4. INI-1 (BAF-47) immunostaining shows loss of nuclear staining in the tumor nuclei and positive in the endothelial cells and residual entrapped pituitary tissue (× 200 magnification).

Table

Table 1. Summary of Previously Described Reports of Sellar AT/RTs and the Present Case
 
YearAge/sexPresentationTreatmentOutcomeReference
1200032/FVisual disturbanceResection, radiation, and chemotherapy28 months (dead)[12]
2200520/FVisual disturbanceResection, radiation, and chemotherapy28 months (survived)[13]
3200531/FNot mentionedResection and radiation9 months (dead)[13]
4200856/FDiplopiaResection and radiation23 months (dead)[14]
5201046/FHeadacheNot mentionedNot mentioned[15]
6201161/FDiplopiaResection3 months (dead)[16]
7201157/FDiplopiaResection, radiation, and chemotherapy6 months (survived)[16]
8201360/FHeadache and diplopiaResection, radiation, and chemotherapy30 months (dead)[17]
9201343/FHeadache and diplopiaResection and radiation2 weeks (survived)[18]
10201444/FVisual disturbanceResection, radiation, and chemotherapy17 months (dead)[19]
11201442/FVisual disturbanceResection, radiation, and chemotherapy27 months (survived)[5]
12201536/FHeadache and blurred visionResection, radiation, and chemotherapy29 months (dead)[20]
13201735/FHeadache, diplopia, and amenorrheaResection, radiation, and chemotherapy37 months (survived)[7]
14Present case40/FHeadache, right oculomotor palsy with decreased visionResection, radiation, chemotherapy2 months