J Neurol Res

Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc

Journal website http://www.neurores.org

Original Article

Volume 9, Number 3, June 2019, pages 23-27

Evaluation of Volume Expansion Therapeutic Effect in Acute Ischemic Stroke

Tables

**Table 1.** Summary of Clinical Data of Patients
	Expansion group (n = 52)	Control group (n = 49)
SD: standard deviation; n: number of cases, M: median; R: range. No significant difference in these clinical data (P > 0.05).
Age (± SD)	58.9 ± 10.8	64.5±13.1
Number of women (n, %)	18 (34.6%)	26 (53.1%)
Past history (n,%)
Hypertension	41 (78.8%)	46 (93.9%)
Diabetes	12 (23.1%)	13 (26.5%)
Coronary heart disease	10 (19.2%)	12 (24.5%)
Atrial fibrillation	1 (1.9%)	1 (2.0%)
Other	1 (1.9%)	2 (4.1%)
Systolic blood pressure at admission (± SD)	155 ± 22	153 ± 23
Systolic pressure at discharge (± SD)	137 ± 18	139 ± 16
NIHSS baseline score (M, R)	5 (3 - 8)	3 (2 - 6)
NIHSS score at discharge (M, R)	3 (1 - 6)	3 (1 - 5)

**Table 2.** Comparison of Treatment Effects Between the Expansion Group and the Control Group
	Expansion group (n, %)	Control group (n, %)	Total (n%)
NIHSS score improvement group	41 (78.8%)	33 (67.3%)	74 (73.3%)
NIHSS score no improvement group	11 (21.2%)	16 (32.7%)	27 (36.5%)
Total	52	49	101

**Table 3.** Evaluation of Factors Affecting the Improvement of NIHSS Score Before and After Treatment
Variable	OR (95% CI)	P value
OR: odds ratio; CI: confidence interval.
Gender	0.577 (0.197, 0.691)	0.316
Age	0.616 (0.203, 0.866)	0.392
Pre-treatment NIHSS score	0.136 (0.014, 0.294)	0.083
Pre-treatment systolic pressure	1.468 (0.402, 5.354)	0.561
Hypertension	0.638 (0.131, 3.109)	0.578
Diabetes	0.816 (0.249, 2.676)	0.737
Coronary heart disease	1.228 (0.310, 4.863)	0.769
Cerebral artery stenosis
No stenosis or mild to moderate stenosis	0.418 (0.040, 4.420)	0.469
Severe stricture	0.225 (0.021, 2.438)	0.220
Treatment	0.693 (0.249, 1.925)	0.481