Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website http://www.neurores.org

Original Article

Volume 6, Number 2-3, June 2016, pages 41-45

Prognostic Value of Hypothalamic Copeptin in Acute Ischemic Stroke

Tables

Table 1. Correlation Between Copeptin Level and Severity of Stroke According to NIHSS
 
NIHSSCopeptin (mean ± SD)TestPost hoc value
Mild (I)7.58 ± 1.76F = 207.46
P value < 0.001		< 0.001 (I vs. II, I vs. III, I vs. IV, II vs. III, II vs. IV, III vs. IV)
Moderate (II)18.12 ± 3.03
Severe (III)26.50 ± 2.39
Very severe (IV)36.0 ± 2.23

 

Table 2. Correlation Between Copeptin Level and Site of Stroke According to OCSP Classification
 
OCSPCopeptin (mean ± SD)TestPost hoc value
PACS (I)17.70 ± 8.58Kruskal-Wallis = 11.11
P value = 0.011		I vs. II = 0.193
I vs. III = 0.783
I vs. IV = 0.015 (S)
II vs. III = 0.290
II vs. IV = 0.004 (S)
III vs. IV = 0.004 (S)
POCS (II)12.90 ± 5.98
LACS (III)15.70 ± 6.98
TACS (IV)28.0 ± 10.12

 

Table 3. Correlation Between the Copeptin Level and Etiological Subtypes of Stroke According to TOAST Classification
 
TOASTCopeptin (mean ± SD)TestPost hoc value
Cardio-embolic (I)12.15 ± 6.24Kruskal-Wallis = 21.19
P value < 0.001		I vs. II < 0.001 (HS)
I vs. III = 0.092
I vs. IV = 0.930
II vs. III = 0.002 (S)
II vs. IV = 0.003 (S)
III vs. IV = 0.141
Large vessel (II)25.50 ± 8.34
Small vessel (III)15.83 ± 6.79
Cryptogenic (IV)12.0 ± 6.0

 

Table 4. Correlation Between the Copeptin Level and Size of Stroke
 
Lesion sizeCopeptin (mean ± SD)Kruskal-WallisP valuePost hoc test
< 1.5 (I) (small)11.10 ± 5.5918.89P < 0.001I vs. II = 0.006
I vs. III < 0.001
II vs. III = 0.047
1.5 - 3 (II) (medium)18.63 ± 8.0
> 3 (III) (large)24.05 ± 8.36

 

Table 5. Relation Between the Outcome of Ischemic Stroke by MRS and Cutoff Point of Copeptin
 
Copeptin levelOutcomeTotal
UnfavorableFavorable
≥ 21.5131023
< 21.503232
Total134255