J Neurol Res

Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc

Journal website http://www.neurores.org

Original Article

Volume 1, Number 3, August 2011, pages 90-95

Hemorrhagic Sensorimotor Stroke: Spectrum of Disease

**Table 1.** Clinical Data, Topography of Lesion, Neurological Findings and Outcome in 12 Patients With Hemorrhagic Sensorimotor Stroke
Sex/Age, Year	Risk Factors	Altered Consciousness	Topography	Outcome
Male/67	Hypertension	No	Internal capsule/basal ganglia	Moderate hemiparesis
Male/67	Hypertension, heavy smoking, obesity, peripheral vascular disease	No	Internal capsule/basal ganglia	Moderate hemiparesis
Female/89	Hypertension	No	Internal capsule/basal ganglia	Mild hemiparesis
Female/77	Hypertension, heavy smoking	No	Internal capsule	Mild hemiparesis
Male/80	Hypertension, congestive heart failure	No	Internal capsule	Mild hemiparesis
Female/73	Hypertension, atrial fibrillation	Yes	Internal capsule	Moderate hemiparesis
Male/78	Hypertension	Yes	Internal caosule/basal ganglia	Mild hemiparesis
Male/78	Hypertension, alcohol abuse	No	Internal capsule/basal ganglia	Mild hemiparesis
Male/57	Hypertension, TIA, hyperlipdemia	No	Internal capsule/basal ganglia	Mild hemiparesis
Female/73	Hypertension, hyperlipidemia	No	Thalamus	Moderate hemiparesis
Female/81	Hypertension, diabetes, TIA, obesity	No	Thalamus	Symptom free
Female/87	Hypertension, TIA	No	Thalamus	Mild hemiparesis

Table 1. Clinical Data, Topography of Lesion, Neurological Findings and Outcome in 12 Patients With Hemorrhagic Sensorimotor Stroke

Sex/Age, Year

Risk Factors

Altered Consciousness

Topography

Outcome

Male/67

Hypertension

Internal capsule/basal ganglia

Moderate hemiparesis

Male/67

Hypertension, heavy smoking, obesity, peripheral vascular disease

Internal capsule/basal ganglia

Moderate hemiparesis

Female/89

Hypertension

Internal capsule/basal ganglia

Mild hemiparesis

Female/77

Hypertension, heavy smoking

Internal capsule

Mild hemiparesis

Male/80

Hypertension, congestive heart failure

Internal capsule

Mild hemiparesis

Female/73

Hypertension, atrial fibrillation

Yes

Internal capsule

Moderate hemiparesis

Male/78

Hypertension

Yes

Internal caosule/basal ganglia

Mild hemiparesis

Male/78

Hypertension, alcohol abuse

Internal capsule/basal ganglia

Mild hemiparesis

Male/57

Hypertension, TIA, hyperlipdemia

Internal capsule/basal ganglia

Mild hemiparesis

Female/73

Hypertension, hyperlipidemia

Thalamus

Moderate hemiparesis

Female/81

Hypertension, diabetes, TIA, obesity

Thalamus

Symptom free

Female/87

Hypertension, TIA

Thalamus

Mild hemiparesis

**Table 2.** Comparison of Patients With Hemorrhagic Sensorimotor Stroke (SMS), Patients With Ischemic SMS and the Remaining Patients With Intracerebral Hemorrhage
Data	Hemorrhagic SMS	Ischemic SMS	P -value^a	Remaining Intracerebral Hemorrhages	P-value^b
Data are n (%) unless otherwise stated. Comparison between ^ahemorrhagic and ischemic sensorimotor stroke;^bhemorrhagic sensorimotor stroke and remaining intracerebral hemorrhages; ^cIsolated (n = 3) or with basal ganglia (n = 6). Total topographies: internal capsule plus basal ganglia 6, internal capsule 3, thalamus 3.
Total patients	12	121		396
Sex, male	6 (50)	61 (50.4)	0.608	208 (52.5)	0.546
Age, years, mean (SD)	75.58 (8.9)	73.6 (12.3)	0.254	72.56 (12.43)	0.225
Age ≥ 85 years	2 (16.7)			67 (16.9)	1.000
Risk factors
Hypertension	12 (100)	85 (70.2)	0.019	235 (59.3)	0.002
Diabetes	1 (8.3)	31 (25.6)	0.164	62 (15.7)	0.423
Atrial fibrillation	1 (8.3)	17 (14)	0.495	61 (15.4)	0.433
Cardiac heart failure	1 (8.3)	3 (2.5)	0.318	8 (2)	0.238
Transient ischemic attack	3 (25)	9 (7.4)	0.078	19 (4.8)	0.022
Previous cerebral infarct	0	16 (13.2)	0.200	36 (9.1)	0.325
Previous hemorrhagic stroke	1 (8.3)	0	0.090	27 (6.8)	0.579
Peripheral vascular disease	2 (16.7)	8 (6.6)	0.223	21 (5.3)	0.142
Obesity	3 (25)	8 (6.6)	0.062	15 (3.8)	0.012
Alcohol abuse	1 (8,3)	6 (5)	0.492	16 (4)	0.404
Smoking (> 20 cigarettes/day)	3 (25)	13 (10.7)	0.159	31 (7.8)	0.069
Hyperlipidemia	2 (16.7)	26 (21.5)	0.517	46 (11.6)	0.423
Clinical findings
Sudden onset	7 (66.7)	45 (37.2)	0.048	236 (59.6)	0.431
Headache	3 (25)	9 (7.4)	0.078	137 (34.6)	0.363
Nausea, vomiting	1 (8.3)	2 (1.7)	0.249	95 (24)	0.183
Speech disorders (dysarthria)	5 (41.7)	39 (32.2)	0.357	140 (35.4)	0.432
Altered consciousness	2 (16.7)	3 (2.5)	0.064	163 (41.2)	0.076
Neuroimaging findings
Thalamus	3 (25)	11 (9.1)	0.115	84 (21.2)	0.490
Internal capsule^c	9 (75)	52 (43)	0.034	64 (16.2)	0.000
Corona radiata	0	7 (5.8)	0.508	3 (0.8)	0.914
Pons topography	0	12 (9.8)	0.305	16 (4)	0.615
Basal ganglia	6 (50)	15 (12,4)	0.004	95 (24)	0.049
Parietal topography	0	0	1	85 (21.5)	0.058
Ventricular	0	0	1.000	95 (24)	0.040
Symptom-free at discharge	1 (8.3)	25 (20.7)	0.275	23 (5.8)	0.522
Urinary complications	2 (16.7)	3 (2.5)	0.064	48 (12.1)	0.979
Infectious complications	1 (8,3)	2 (1.7)	0.249	84 (21.2)	0.471
Respiratory complications	2 (16.7)	4 (3.3)	0.092	46 (11.6)	0.593
Length of hospital stay, mean (SD)	18.5 (7.9)	14.9 (8.9)		21.1 (21)	0.125
In-hospital mortality	0	0	1.000	112 (28.3)	0.042

Table 2. Comparison of Patients With Hemorrhagic Sensorimotor Stroke (SMS), Patients With Ischemic SMS and the Remaining Patients With Intracerebral Hemorrhage

Data

Hemorrhagic SMS

Ischemic SMS

P -value^a

Remaining Intracerebral Hemorrhages

P-value^b

Data are n (%) unless otherwise stated. Comparison between ^ahemorrhagic and ischemic sensorimotor stroke;^bhemorrhagic sensorimotor stroke and remaining intracerebral hemorrhages; ^cIsolated (n = 3) or with basal ganglia (n = 6). Total topographies: internal capsule plus basal ganglia 6, internal capsule 3, thalamus 3.

Total patients

121

396

Sex, male

6 (50)

61 (50.4)

0.608

208 (52.5)

0.546

Age, years, mean (SD)

75.58 (8.9)

73.6 (12.3)

0.254

72.56 (12.43)

0.225

Age ≥ 85 years

2 (16.7)

67 (16.9)

1.000

Risk factors

Hypertension

12 (100)

85 (70.2)

0.019

235 (59.3)

0.002

Diabetes

1 (8.3)

31 (25.6)

0.164

62 (15.7)

0.423

Atrial fibrillation

1 (8.3)

17 (14)

0.495

61 (15.4)

0.433

Cardiac heart failure

1 (8.3)

3 (2.5)

0.318

8 (2)

0.238

Transient ischemic attack

3 (25)

9 (7.4)

0.078

19 (4.8)

0.022

Previous cerebral infarct

16 (13.2)

0.200

36 (9.1)

0.325

Previous hemorrhagic stroke

1 (8.3)

0.090

27 (6.8)

0.579

Peripheral vascular disease

2 (16.7)

8 (6.6)

0.223

21 (5.3)

0.142

Obesity

3 (25)

8 (6.6)

0.062

15 (3.8)

0.012

Alcohol abuse

1 (8,3)

6 (5)

0.492

16 (4)

0.404

Smoking (> 20 cigarettes/day)

3 (25)

13 (10.7)

0.159

31 (7.8)

0.069

Hyperlipidemia

2 (16.7)

26 (21.5)

0.517

46 (11.6)

0.423

Clinical findings

Sudden onset

7 (66.7)

45 (37.2)

0.048

236 (59.6)

0.431

Headache

3 (25)

9 (7.4)

0.078

137 (34.6)

0.363

Nausea, vomiting

1 (8.3)

2 (1.7)

0.249

95 (24)

0.183

Speech disorders (dysarthria)

5 (41.7)

39 (32.2)

0.357

140 (35.4)

0.432

Altered consciousness

2 (16.7)

3 (2.5)

0.064

163 (41.2)

0.076

Neuroimaging findings

Thalamus

3 (25)

11 (9.1)

0.115

84 (21.2)

0.490

Internal capsule^c

9 (75)

52 (43)

0.034

64 (16.2)

0.000

Corona radiata

7 (5.8)

0.508

3 (0.8)

0.914

Pons topography

12 (9.8)

0.305

16 (4)

0.615

Basal ganglia

6 (50)

15 (12,4)

0.004

95 (24)

0.049

Parietal topography

85 (21.5)

0.058

Ventricular

1.000

95 (24)

0.040

Symptom-free at discharge

1 (8.3)

25 (20.7)

0.275

23 (5.8)

0.522

Urinary complications

2 (16.7)

3 (2.5)

0.064

48 (12.1)

0.979

Infectious complications

1 (8,3)

2 (1.7)

0.249

84 (21.2)

0.471

Respiratory complications

2 (16.7)

4 (3.3)

0.092

46 (11.6)

0.593

Length of hospital stay, mean (SD)

18.5 (7.9)

14.9 (8.9)

21.1 (21)

0.125

In-hospital mortality

1.000

112 (28.3)

0.042