Blindness or Agnosia: Review of Posterior Cortical Atrophy and a Difficult Case

Bo Biering-Sorensen, Moa Gustafsson, Jesper Gyllenborg, Ian Law, Peter Hogh

Abstract


    The Objective was to briefly review the rare condition Posterior Cortical Atrophy (PCA) and demonstrate a difficult case suffering from both visual disturbances due to glaucoma and visual agnosia due to PCA. The short review was made by Pub Med search including “Posterior Cortical Atrophy” and the reference lists from the obtained articles were scrutinized for relevant literature not retrieved from PubMed. PCA is a slowly progressing neurodegenerative disorder that is very disabling due to disturbances of higher visual functions, although memory might be relatively preserved until late in the course. Some previous authors have underscored, that to diagnose a patient with PCA one must rule out that the patient is suffering from an eye disease. We demonstrate a difficult case suffering from both glaucoma and PCA. The diagnostic characteristics for PCA are described, and neuroimaging including positron emission tomography (PET) with the amyloid binding ligand (11C) Pittsburgh compound B (PiB), and results from treatment of PCA are presented. Caution should be advised when patients with impaired visual acuity develop signs of cognitive dysfunction, and a full neuropsychological examination should be performed whenever there is doubt of the significance of visual impairment and impaired visuospatial functions.




doi:10.4021/jnr91w

Keywords


Posterior cortical atrophy; Visual agnosia; Glaukoma; Cholinesterase inhibitor; PiB-PET

Full Text: HTML PDF
 
Home     |     Log In     |      About     |      Search     |      Current     |      Archives     |      Submit      |     Subscribe


 

     

Aims and Scope

Current Issues

Conflict of Interest

About Publisher

Editorial Board

Archives

Copyright

Company Profile

Editorial Office

Misconduct and Retraction

Permissions

Company Registration

Contact Us

Abstracting and Indexing

ICMJE

Ownership

Instructions to Authors

Access

Declaration of Helsinki

Contact Publisher

Submission Checklist

Reprints

Terms of Use

Company Address

Submit a Manuscript

Open Access Policy

Privacy Policy

Browse Journals

Publishing Fee

Publishing Policy

Disclaimer

Recent Highlights

Peer-Review Process

Publishing Quality

Code of Ethics

Advertising Policy

Manuscript Tracking

Advanced Search

For Librarians

Careers

Publishing Process

Publication Frequency

For Reviewers

Propose a New Journal

       
       

Journal of Neurology Research, bimonthly, ISSN 1923-2845 (print), 1923-2853 (online), published by Elmer Press Inc.     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.neurores.org   editorial contact: editor@neurores.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

DECLARATION: THIS JOURNAL SITE OUTLOOK IS DESIGNED BY THE PUBLISHER AND COPYRIGHT PROTECTED. DO NOT COPY!