Adrenal Ganglioneuroma With Lymph Node Deposits: A Rare Benign Tumor

Abstract

     Ganglioneuromas are rare, benign tumors arising from primordial neural crest cells. We report a case of a seven-year-old girl presenting with a history of pain in the left side of the abdomen since one year. A provisional diagnosis of a non-functioning adrenal tumor was made on the basis of radiological scans and endocrine profile. The specimen was excised along with a lymph node. The specimen showed a grey white lesion measuring 2.5 x 2.5 cm. Sections from the lesion and the lymph node showed a benign tumor with spindle cells in intersecting fascicles and ganglion cells in clusters. A final diagnosis of benign ganglioneuroma was thus made. Adrenal gland ganglioneuromas with lymph node deposits represent a spontaneous differentiation from neuroblastoma in which the lymph node deposit has also matured. Representation of this entity in literature is important to alert the histopathologist for the diagnosis of a benign tumor in the primary and metastatic site.



doi:10.4021/jnr56e